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Services

Respiratory diseases

Our respiratory diseases models include asthma, acute lung injury, lung fibrosis, COPD and cough. 


Animal Disease Models

           Asthma
           • Ovalbumin-induced asthma in rats and mice
           • Ovalbumin-induced asthma in non-human primates
           • House dust mite-induced asthma in rats and mice
           • House dust mite-induced asthma in non-human primates


           Acute Lung Inflammation
           • LPS-induced acute lung inflammation in rats and mice
           • LPS-induced acute lung inflammation in non-human primates


           Lung Fibrosis
           • A single dose of bleomycin-induced asthma in rats and mice
           • Multiple doses of bleomycin-induced asthma in rats and mice


           Cough
           • Citric acid-induced cough in guinea pigs



           Endpoints:

             - H&E staining                                               

             - Cytokines and Biomarkers
             - Masson Trichrome staining                                              

             - Inflammatory Cell Counts in BALF
             - Periodic acid Schiff staining                                             

             - Airway hyperreactivity
             - Immunochemistry                                                             

             - Cough number recording
             - Hydroxyproline content