Technotes

Technotes

DMPK Services

PharmaLegacy Models and Research Tools



PharmaLegacy can provide a complete complementary PK/ADME service. Our team of DMPK scientists are dedicated to both discovery and development. This coupled with state-of-the-art instrumentation and supported by an AAALAC accredited vivarium, assists our clients from lead candidate selection through development and ensures a high quality of DMPK studies with cost-efficiency and fast turnaround.

 

 

Case Study  1 -  PK Profiling in Rodent, Non-human Primate and Canine

 

PK profiling of ANA-088 in SD rats (n=5, A), cynomolgus monkeys (n=3, B) and beagle dogs (n=3, C) after a single dose


Case Study  2 -  PK-PD Study in Hamster


PK-PD study of ANA-077 on high cholesterol diet-induced hyperlipidemia in hamsters


Note:

All values in PD: Mean +/- SEM; HCD, high cholesterol diet; TC, total cholesterol; TG: triglyceride; HDL-c, HDL-bound cholesterol.