UVEITIS & CONJUNCTIVITIS MODELS

Delivering translatability in autoimmunity models.

Uveitis and conjunctivitis can both lead to worrisome ocular complications. Synechia, retinal scarring, and spreading of the infection to the cornea, lids, and tear ducts are some of the many exacerbations that untreated uveitis and conjunctivitis can potentially develop into. Certain autoimmune diseases, namely Rheumatoid Arthritis (RA) and Systemic Lupus Erythematosus (SLE) happen to have ocular manifestations in their early presentations, which further justifies the search for accurate and translatable uveitis and conjunctivitis models.

Look no more.

Whether you are taking on clinical or basic studies of ocular and organ-specific autoimmunity, your choice of CRO is crucial in regard to the outcome of your study. Put your mind at ease: work with PharmaLegacy.

Contact Us
Uveitis / Conjunctivitis

MODELS / SERVICES

Case: Compounds on Bovine IRBP R16-Induced EAU in Lewis Rats

Experimental Procedures

·         Animal species and strain: Lewis rats

·         History of treatment: naive

·         Food: free access to food

·         Water: free access to water

·         Reagents: IRBP R16 solution/ Modified Complete Freund’s Adjuvant (CFA)

Experimental Results


Effect of FTY-720 on Bovine IRBP R16-Induced EAU in Lewis Rats


Histopathology Photo

Case: Compounds on Experiment Allergic Conjunctivitis

Experimental Procedures

· Animal species and strain: BALB/c mice

· History of treatment: Naive

· Sex, age and weight: Female, 6 – 8 weeks.

· Food: Free access to food

· Water: Free access to water

· Reagent: Ovalbumin (OVA)/ Inject Alum hydroxide solution

 

Total Score of Hyperemia and Edema

Count of Eye Scratching

Histopathological Eosinophils Detection

Committed to quality:

  • AAALAC and CNAS guidelines-adherent animal studies
  • Remote real-time monitoring of studies
  • Electronically managed, traceable research data
  • 43,000 square feet of vivarium space

Choose quality above all. Choose PharmaLegacy.

Contact Us

Can you trust your animal model to provide you with the correct answers?

No animal study can predict with complete certainty how a therapy will perform in human subjects, but it is PharmaLegacy’s job to ensure that you come as close to certainty as possible. Download our brochure on non-human primate (NHP) models and see how PharmaLegacy ensures that your studies utilize the most physiologically relevant models.





    Immune NHP Models Brochure

    We’re ready when you are.

    Tell us your pharmacology challenges.