XENOGRAFT MOUSE MODELS

When personalized medicine calls for high fidelity tools.

Xenograft mouse models are mainly used to assess the multiple factors involved in the development of malignant tumors (transformation and invasion), how they metastasize, and their response to different types of treatments. The advantages of using xenograft models are too many to be listed, but some noteworthy examples are the simplicity of the grafting technique, the preservation of both tumor heterogeneity and lineage hierarchy, and the possible future applications in personalized precision medical treatments.

At PharmaLegacy, we are aware that your pipeline might lead to the next breakthrough in cancer therapies, so your studies need to be conducted with the utmost care. Our team of experts is ready to provide you with the answers you need to take your pipeline all the way. When thousands of lives depend on your work, depend on PharmaLegacy.

Xenograft Mouse Models

MODELS / SERVICES

PharmaLegacy has developed 367 PDX models covering 6 cancer types with full information of diagnosis and treatment history, more is under development.

  • Patient information with diagnosis and treatment history
  • 359 PDX models covering 6 cancer types and more ongoing

PDX Models: Gastric Cancer Profile

Gastric Orthotopic Model

Liver Orthotopic Model

Orthotopic Model: CC-090010-3 (Colon)

Our models include:



Case Study:

HT-29 Intrasplenic Implantation – Liver Metastasis
Animal: 16 nude mice (from SLAC), 6~7 weeks, female

Tumor Cell: HT-29(P4, 1*106 per mouse), intrasplenic implantation

 

Committed to quality:

  • AAALAC accredited vivarium
  • PK/PD, molecular pharmacology and preliminary toxicology adjacency studies
  • 24/7 access to PharmaLegacy representatives
  • Research data electronically managed by BioBook (IDBS, UK)

Want your scientific discoveries to become treatments? PharmaLegacy’s the right partner for you.

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Top Pharmaceutical Companies Trust PharmaLegacy for their Oncology Trials

“The study they delivered on a very reasonable budget was top notch […] The model was executed flawlessly.”

See why a top-20 pharmaceutical company trusts PharmaLegacy for their preclinical immuno-oncology trials.





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