PK Studies

Unwavering quality in PK studies

Animal PK studies are valuable tools for screening compounds during the candidate optimization stage of drug discovery. PK studies provide valuable information on compounds including exposure, AUC, clearance, and half-life, etc. Proper PK studies can help speed up discovery, and ensure only compounds with desirable PK profiles are advanced into the clinic.

At PharmaLegacy, we perform whole ranges of animal PKs with species ranging from rodents to non-human primates (NHPs). We have more than a decade of experience servicing clients worldwide. Our vivarium is AAALAC accredited.

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WT Mouse: CD-1, C57BL/6, BALB/c, Nude Mouse

Transgenic Mouse

Rat: SD, Wistar Han

Guinea Pig


Case Study: Large Molecule PK in Mouse

Case Study: Cassette Dosing PK in Mouse

Dog: Beagle

Monkey: Cynomolgus

Rabbit: New Zealand

Minipig: Bama

Case Study: Large Molecule PK in Monkey

Single Dose

Repeat Dose

Intravenous (Bolus and Infusion)

Oral (Solution, Suspension, Tablet, Capsule)








5 working days for single period studies for 90% of studies.

AUC, Half-life, Clearance, etc.

PK Calculation with WinNonlin

Extensively validated preclinical models:

  • Completed over 400 FDA / CFDA IND filings
  • Scientific staff with an average of over 15 years of experience in pharmacology
  • PK/PD, molecular pharmacology and preliminary toxicology adjacency studies
  • Capacity to house over 30,000 rodents and large animals

Work with the CRO that has the most experience in pharmacology. Work with PharmaLegacy.

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We’re ready when you are.

Tell us your pharmacology challenges.