INFLAMMATION AND IMMUNE DISEASE MODELS
Rigorous inflammation and immune disease models.
In 2008, the mummy of king Mernepath, an egyptian pharaoh who ruled over Egypt some 3,200 years ago was put under investigation along with other mummies to confirm their cause of death, which was hypothesized to be atherosclerosis. Surprisingly, all mummies showed fatty buildups in their arteries. Atherosclerosis, an inflammatory disease affecting 101 in 1000, was always thought to be caused by modern lifestyles: smoking, diabetes, a sedentary lifestyle, etc., none of which were prevalent 3,200 years ago.
If there is one thing the scientific method has taught us at PharmaLegacy, it’s skepticism. Some inflammatory and immune diseases have been described in the literature for ages. Yet sometimes, mummies that were left untouched for thousands of years prove to us that we should always remain skeptical: nothing is written in stone in science. Whether you are trying to bolster established literature, or challenge what was once thought to be written in stone, PharmaLegacy has your back!
MODELS / SERVICES
Case Study：TTx-Induced DTH in Cynomolgus Monkey
Case Study：Chemotherapy-Induced Mucositis in Cynomolgus Monkey
DSS-Induced Colitis in Cynomolgus Monkey
Collagen II-Induced Arthritis (CIA) in Cynomolgus Monkey
I.V. LPS-Induced Cytokines Production in Cynomolgus Monkey
Case Study：LPS-Induced Systemic Inflammation Model
Case Study: Anti-inflammatory activity of the bradykinin B1R antagonist in a model of LPS-induced lung inflammation in the cynomolgus monkey
Striving for excellence:
- Completed over 400 FDA / CFDA IND filings
- AAALAC and CNAS guidelines-adherent animal studies
- FDA Part 11 compliant
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