PHARMACOKINETICS (PK) STUDIES IN RODENTS, RABBITS, CANINES, PIG AND NON-HUMAN PRIMATES

Reliable quantitative studies for your pipelines.

Absorption, Distribution, Metabolism and Excretion. These processes, better known by their acronym, ADME, when analyzed all together, describe a drug’s overall disposition through pharmacokinetics. The importance of pharmacokinetic studies are invaluable; they give us a quantitative insight of what the body does to a drug. If you are reading this, you are probably developing a new drug, and want to take the next step with PK studies.

Here’s an offer you can’t refuse: PK studies designed by our experts, at PharmaLegacy, who have been doing this for more than 15 years already. Our staff has kept over half of the top 20 pharmaceutical companies satisfied for years in a row. Join them. Get in touch now!

Contact Us
Pharmacokinetics / ADME

MODELS / SERVICES

In Vivo Pharmacokinetic Study

In Vivo Dosing

  • Intravenous (bolus/infusion)
  • Oral, subcutaneous, intramuscular, intradermal, plus other route
  • Intra-duodenal, intra-portal

Species

  • Rodent
  • Canine
  • Non-human primate
  • Rabbit
  • Guinea pig

Outputs

  • Sample concentrations
  • PK parameters (WinNonLin)

Services

  • Bioavailability
  • Single and multiple dose PK
  • Dose ranging and proportionality
  • Cassette PK for compound screening
  • Drug distribution in tissues
  • PK study for formulation/form development
  • Exploratory non-GLP TK studies
  • PK/PD study in animal disease models
  • PK study for IND filing
  • ADA assays in non-human primate

Instrument

  • LC-MS/MS (API4000)
  • HPLC-UV (Agilent 1200)
  • Micro-plate reader

Case Study: PK Study for Large Molecule Drug in Monkey (ELISA)

 

Faultless preclinical models:

  • 600+ validated animal models of disease spanning 40+ diseases
  • Scientific staff with an average of over 15 years of experience in pharmacology
  • PK/PD, molecular pharmacology and preliminary toxicology adjacency studies
  • 150,000 square feet of facility space

If you are looking for comprehensive preclinical development services, you came to the right place. Get in touch with our team of highly trained professionals and let’s get your pipeline moving.

Contact Us

We’re ready when you are.

Tell us your pharmacology challenges.