discovery toxicology studies

Leading the waltz between therapeutic levels and toxic side effects.

Discovery Tox

Discovery Tox is one of the most important tools to assess the potential toxicity profiles of compounds of interest during the discovery stage. When many pharmaceutical companies are adopting the strategy of “kill early, fail cheaply”, discovery tox results become critically important deciding factors when selecting compound for IND.

At PharmaLegacy, we have been providing discovery tox services to clients to speed up their drug discovery process with drug modalities ranging from small molecule, peptide, mAb, and ADC, to gene therapy.

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Rodent: Mouse, Rat

Dog: Beagle Dog

Monkey: Cynomolgus Monkey

Rabbit: New Zealand Rabbit

Single Dose

Repeat Dose

Intravenous (Bolus and Infusion)

Oral (Solution, Suspension, Tablet or Capsule)





Cage-side Observation and Detailed Clinical Observation

Food / Water Consumption

Body Weight

Clinical Pathology

Macroscopic Observation



Extensively validated preclinical models:

  • FDA Part 11 compliant
  • 380,000 square feet of facility space
  • Capacity to run 200+ concurrent animal studies
  • 1,000+ validated animal models available immediately; start your study in under two weeks!
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We’re ready when you are.

Tell us your pharmacology challenges.